The founding team

KarMac was built by a multidisciplinary group of scientific inventors, expert oncologists, and engineers dedicated to solving one of the hardest challenges in cancer treatment. We are united by a shared mission to break down the biological barriers of solid tumors and unlock the body's natural immune response.

Rooted in deep myeloid biology, our leadership draws on extensive translational expertise from institutions like Harvard and Mount Sinai. By combining clinical insights with cutting-edge cellular engineering, the founding team is pioneering a completely new class of immuno-oncology therapies to bring transformative results to patients.

Jennifer Guerriero

PhD
Lead Investigator / Scientific Inventor
Associated Institutions
The Guerriero Lab, Brigham and Women's Hospital, Harvard Medical School

Thomas Marron

MD, PhD
Director of the Early Phase Trials Unit
Associated Institutions
Icahn School of Medicine at Mount Sinai

Daniel Michaud

PhD
Postdoctoral Fellow / Scientific Inventor
Associated Institutions
The Guerriero Lab, Brigham and Women's Hospital, Harvard Medical School

Alex Gottlieb

Scientist
Associated Institutions
The Guerriero Lab, Harvard John A. Paulson School of Engineering and Applied Sciences

A first-in-class CAR-Monocyte immuno-oncology platform.